This paper relates Donaldson and Dunfee’s Integrative Social Contracts Theory to the problem of gender discrimination. We make the assumption that multinational managers might seek some guidance from ISCT to resolve ethical issues of gender discrimination in countries indifferent or hostile to gender equaIity. The role of Donaldson and Dunfee’s “hypernorms” seems especially cruciaI, and we find that, under their writings thus far, no “hypernorms” exist to make unethical the most blatant acts of sex discrimination in a host country whose (...) local norms tolerate such discrimination. The genesis of “hypernorms” as “global moral minimums” is recounted, and specific application of ISCT to a familiar ethics case (“A Foreign Assignment”) is provided. (shrink)

One of the main challenges in medicine is to guarantee an appropriate drug supply according to the real needs of patients. Closed-loop strategies have been widely used to develop automatic solutions based on feedback variables. However, when the variable of interest cannot be directly measured or there is a lack of knowledge behind the process, it turns into a difficult issue to solve. In this research, a novel algorithm to approach this problem is presented. The main objective of this study (...) is to provide a new general algorithm capable of determining the influence of a certain clinical variable in the decision making process for drug supply and then defining an automatic system able to guide the process considering this information. Thus, this new technique will provide a way to validate a given physiological signal as a feedback variable for drug titration. In addition, the result of the algorithm in terms of fuzzy rules and membership functions will define a fuzzy-based decision system for the drug delivery process. The method proposed is based on a Fuzzy Inference System whose structure is obtained through a decision tree algorithm. A four-step methodology is then developed: data collection, preprocessing, Fuzzy Inference System generation, and the validation of results. To test this methodology, the analgesia control scenario was analysed. Specifically, the viability of the Analgesia Nociception Index as a guiding variable for the analgesic process during surgical interventions was studied. Real data was obtained from fifteen patients undergoing cholecystectomy surgery. (shrink)

El llamado “pacto de postguerra” fue una de las mayores transformaciones institucionales de la historia europea que delimitó los cauces por los que discurrió su política durante varias décadas. En este artículo se ofrece, primero, una descripción de los fundamentos básicos del pacto que ahonda particularmente en el caso británico. En segundo lugar, se aborda el debate socialista británico que generó esta reforma del capitalismo. El desafío del ala derecha del laborismo fue replicado por los miembros del Partido Comunista de (...) Gran Bretaña y de la primera New Left. Se reconstruyen aquí los argumentos del debate prestando especial atención a los disputados conceptos de “democracia”, “propiedad” y “socialismo”. (shrink)

This work focuses on the application of machine learning techniques to assist the clinicians in the administration of analgesic drug during general anaesthesia. Specifically, the main objective is to propose the basis of an intelligent system capable of making decisions to guide the opioid dose changes based on a new nociception monitor, the analgesia nociception index. Clinical data were obtained from 15 patients undergoing cholecystectomy surgery. By means of an off-line study, machine learning techniques were applied to analyse the possible (...) relationship between the analgesic dose changes performed by the physician due to the hemodynamic activity of the patients and the evolution of the ANI. After training different classifiers and testing the results under cross validation, a preliminary relationship between the evolution of ANI and the dosage of remifentanil was found. These results evidence the potential of the ANI as a promising index to guide the infusion of analgesia. (shrink)

Urban communities in 21st century America are facing severe economic challenges, ones that suggest a mandate to contemplate serious changes in the way America does business. The middle class is diminishing in many parts of the country, with consequences for the economy as a whole. When faced with the loss of its economic base, any business community must make some difficult decisions about its proper role and responsibilities. Decisions to support the community must be balanced alongside and against responsibilities to (...) owners, shareholders and relevant “stakeholders” in a relatively new context. Corporations in urban communities “hollowed out” by white flight or urban sprawl must decide what level of support they can and should provide. This paper examines corporate decisions within the emerging urban prosperity initiatives, using the framework of integrative social contract theory proposed by Donaldson and Dunfee. We suggest that urban prosperity initiatives present a mandate on corporations sufficiently strong as to qualify as an authentic norm. Further, we argue that strict adherence to a corporate bottom line approach or “corporate isolationism” is not congruent with contemporary community standards. (shrink)

El objetivo de este artículo es proporcionar algunas claves históricas y conceptuales para comprender la historia del socialismo británico libertarian y su relación con la concepción fiduciaria del poder político y del poder económico. Las expresiones de este socialismo no son homogéneas, convivieron con otras ideas rivales llegando en ocasiones a mezclarse con ellas; y fueron formuladas siempre como respuestas concretas ante los problemas que planteaba cada momento histórico. Desde el socialismo republicano de algunos seguidores de Robert Owen hasta los (...) desafíos que planteó la New Left, las teorías fiduciarias encontraron hueco para abrirse paso en los escritos de estos socialistas libertarian. The objective of this paper is to provide some historical and conceptual keys to understand the history of libertarian British socialism, and its relationship with the fiduciary conception of political power and economic power. The expressions of this libertarian socialism are not homogeneous, they coexisted with other rival conceptions, sometimes mixing with them. Those articulations were always formulated as concrete responses to the problems laid out by different historical moments. From the republican socialism of some Robert Owen’s followers to the challenges exposed by the New Left, fiduciary theory found room to break through in the writings of these libertarian socialists. (shrink)

El presente artículo analiza la conexión humana que acaece en el proceso cinematográfico. Se analiza la conexión desde su capacidad de influencia: emisores y receptores se influyen mutuamente. Se abandona así una concepción mecánica y lineal de la conexión para abordar una conexión más humana y polidireccional. En este sentido, se muestra que, desde una perspectiva productiva, perceptiva y cognitiva, el proceso cinematográfico implica la existencia, en mayor o menor grado, de interacción entre autores, contexto y público. Para comprender cómo (...) tiene lugar la conexión en el cine, se examina desde el psicoanálisis, la sociología y la filosofía del proceso de identificación. Se analizan en detalle seguidamente los distintos procesos humanos de conexión que suceden en el cine, prestando especial atención a la existente entre: emisores/autores y receptores/público, por medio del objeto cinematográfico, la película. (shrink)

L’article inscrit la guerre d’Ukraine dans le cadre d’une politique clausewitzienne de contre-révolution mondiale. Cette guerre interétatique est le résultat du cycle de déploiement des printemps et des soulèvements de la dernière décennie et a des répercussions synchroniques sur un clivage interne qui traverse d’autres pays. L’article se conclut par une vision alternative entre un conflit inter-impérialiste dans lequel l’Europe est menacée par le bloc atlantiste et une dichotomie autocraties/démocraties.

À partir d’auteurs comme Negri, Cocco, Viveiros de Castro et Fanon, cet article discute le devenir-indien comme un concept pour les forces expressives de luttes et de réinvention dans le Sud. À travers de formes concrètes d’intervention, on analyse un mode de résistance à la fois créatif et alternatif, qui prend le contre-pied de l’actuel agenda capitaliste et néo-développementiste.

Advances in genomics have led to calls for developing population-based preventive genomic sequencing programs with the goal of identifying genetic health risks in adults without known risk factors. One critical issue for minimizing the harms and maximizing the benefits of PGS is determining the kind and degree of control individuals should have over the generation, use, and handling of their genomic information. In this article we examine whether PGS programs should offer individuals the opportunity to selectively opt out of the (...) sequencing or analysis of specific genomic conditions or whether PGS should be implemented using an all-or-nothing panel approach. We conclude that any responsible scale-up of PGS will require a menu approach that may seem impractical to some, but that draws its justification from a rich mix of normative, legal, and practical considerations. (shrink)

U.S. multinational enterprises must now follow the policies of Title VII of the Civil Rights Act of 1964 in their overseas operations, at least with respect to U.S. expatriate employees. Doing so in a culture which discourages gender equality in the workplace raises difficult issues, both practically and ethically. Vigorously importing U.S. attitudes toward gender-equality into a social culture such as Japan or Saudi Arabia may seem ethnocentric, a version of ethical imperialism. Yet adapting to host country norms risks a (...) kind of moral relativism. This article supports the view that MNEs which promote workplace equality in a host country such as Japan, which is actively involved in the international economic and political community, is not ethical imperialism in any pejorative sense and is preferable to a moral relativism or social contract approach.We hold these truths to be self-evident: that all men are created equal, and endowed by their creator with certain rights — life, liberty, and the pursuit of happiness. (shrink)

One of the most pleasurable aspects of video games is their ability to induce immersive experiences. However, there appears to be a tentative conceptualization of what an immersive experience is. In this short review, we specifically focus on the terms of flow and immersion, as they are the most widely used and applied definitions in the video game literature, whilst their differences remain disputable. We critically review the concepts separately and proceed with a comparison on their proposed differences. We conclude (...) that immersion and flow do not substantially differ in current studies and that more evidence is needed to justify their separation. (shrink)

This paper examines how the application of legal fiduciary principles , can serve as a framework to promote management of clinical genomic “incidental” or secondary target findings that is patient-centered and consistent with recognized patient autonomy rights. The application of fiduciary principles to the clinical genomic testing context gives rise to at least four physician fiduciary duties in conflict with recent recommendations by the American College of Medical Genetics and Genomics . These recommendations have generated much debate among lawyers, clinicians, (...) and bioethicists hence I believe this publication will be of value and interest to your readership. (shrink)

In their article “Implementing Expanded Prenatal Genetic Testing: Should Parents Have Access to Any and All Fetal Genetic Information?” Bayefsky and Berkman briefly mention that: “[s]ome are...

The intersection of ethics, computing, and genetics plots a space not yet adequately mapped, despite its importance, indeed, its rapidly growing importance. Its subdomains are well-enough known: or the study of ethical issues in genetics and genomics, is part of core curricula everywhere. Ethics and computing is an established subfield. Computing and geneticshas in little more than a decade progressed from subsubspecialty to the sine qua non of contemporary biomedical research, and it bids fair to transform clinical practice. We must (...) prepare for the complete digitization of the genomes of individual patients and the storage of millions of these genomes in very large databases. (shrink)

Volume 19, Issue 7, July 2019, Page 34-36.

Descartes consolida el paso de la ciencia de la verdad a la ciencia del hombre. En esta prima un cura sui, que acabará fortaleciendo al sujeto interiormente y desenfocando al otro. Todo hombre podría ser sabio; si bien, no desde la experiencia de la conciencia como ejercicio metódico y teórico del alma; pero sí como forma de vida que educa el fortalecimiento de la voluntad. La generosidad será la forma de la virtud, y si bien esta incluye las formas del (...) amor, el cogito cartesiano no logra salir de la auto-referencialidad. (shrink)

Nature of natura: un approach on mystic and science in peninsular Iberian medieval Franciscanism The present paper shows the relationship between the concepts Natura and Nature at Castillan Court and Franciscan Peninsular thinking on XIII century. Especially we study this distinction in Juan Gil de Zamora wisdom methodology of natural philosophy, equilibrating science, and mystical approach.

El trabajo presenta las distintas actividades científicas que con motivo del cuarto centenario del fallecimiento de Francisco Suárez se han celebrado y se han organizado durante el año 2017 o el curso académico 2017-18. En las iniciativas presentadas se advierte la vigencia de la reflexión suareciana, no sólo por su relevancia histórica, sino también como un pensamiento con el que poder replantear los retos de nuestra situación contemporánea.

Los artículos de este segundo número monográfico dedicado a Descartes son un fruto más del proyecto de investigación -financiado por el Ministerio de Ciencia e Innovación, [Referencia PID2021-126133NB-I00]- que lleva por título: Éticas y metafísica de los afectos. Las génesis modernas del presente actual (EMAP). Se ofrecen a continuación relecturas cartesianas que ponen el acento en la revisión de ciertos tópicos atribuidos al pensamiento del padre de la modernidad, más mencionado que leído y estudiado.

This book proposes a shift in the very concept of neoliberalism as an ambivalent product of subjectivity. It is not resolved in dichotomies between the included and excluded, interior and exterior, capitalist and noncapitalist. Neoliberalism operates in blurred lines, through flexible structures, and amid internal gradients and varying tensions.

The first contribution of this article is a politico-philosophical map that, drawing upon two common sets of arguments against modern natural rights, might help to explain the prevailing neo-republican position on natural rights. Under the label ‘abstraction argument’, we explore the view that natural rights are a metaphysical construct that usually ends in a violent application of speculative principles to society. Under ‘self-interest argument’, we discuss the notion that natural rights endorse an atomistic and selfish conception of the human being. (...) Second, we show how Cold War authors replicated these two arguments, conveying a biased, largely anti-republican and anti-democratic view of natural rights to the twentieth century. Third, drawing on these two arguments, we critically assess the narrow view of natural rights inherited by neo-republican scholars. (shrink)

Automatic control of physiological variables is one of the most active areas in biomedical engineering. This paper is centered in the prediction of the analgesic variables evolution in patients undergoing surgery. The proposal is based on the use of hybrid intelligent modelling methods. The study considers the Analgesia Nociception Index to assess the pain in the patient and remifentanil as intravenous analgesic. The model proposed is able to make a one-step-ahead prediction of the remifentanil dose corresponding to the current state (...) of the patient. The input information is the previous remifentanil dose, the ANI variable and the electromyogram signal. Modelling techniques used are Artificial Neural Networks and Support Vector machines for Regression combined with clustering methods. Both training and validation were done with a real dataset from different patients. Results obtained show the potential of this methodology to calculate the drug dose corresponding to a given analgesic state of the patient. (shrink)

Los textos que se presentan a continuación aúnan a reconocidos estudiosos en el cartesianismo, junto a investigadores más nóveles. Son fruto además de un proyecto de investigación financiado por el Ministerio de Ciencia e Innovación, [Referencia PID2021-126133NB-100] que lleva por título: Éticas y metafísica de los afectos. Las génesis modernas del presente actual (EMAP). Se ofrecen, por tanto, los estudios que siguen como resultados de este proyecto, que inició su andadura en septiembre de 2022.

El día dieciséis de julio de este año, un día después de la festividad de san Buenaventura, este santo franciscano, doctor de la Iglesia, recibió un regalo: una de las personas que aquí y ahora más conocía de su obra, pensamiento y fuentes, iba a ir a visitarlo. Ambos tenían, al fin, la oportunidad de conocerse en persona. Para sus amigos fue un regalo muy caro. Nuestro amigo Francisco de Asís Clavero Blanco nos dejó físicamente, pero sus estudios y su (...) obra perdura y perdurará con nosotros.' Decir que alguien conoce a san Buenaventura no es fácil, pues en este pensador franciscano se conjugan aspectos filosóficos, teológicos, históricos y espirituales que llevan en sí una carga histórica compleja que se desarrolla en un tiempo, a la vez, complejo, apasionante y alejado en el tiempo: el siglo XIII. No en vano, la figura de san Buenaventura fue tildada por algunos como "la más medieval de la filosofía del Medioevo".Pero Francisco de Asís Chavero se preparó para afrontar este reto y más. Nacido en Rivera del Fresno en 1945, profesó en la Orden Franciscana en la Provincia Bética el 6 de agosto de 1967. Se ordenó presbítero el 21 de julio de 1973. Cursó filosofía y teología en el Centro de Estudios Teológicos de Sevilla, en la Facultad de Teología de Granada, en el Pontificio Ateneo Antonianum y en el Centro de Investigación de Quarachi de la Orden Franciscana situada en Grottaferrata en Roma. Estos estudios hicieron que quedara corta su titulación de Licenciado en S. Teología, sección Histórico?Dogmática. En el momento en el que le sorprendió la muerte era profesor de Teología Sistemática, Antropología Teológica y Pensamiento Franciscano en el Instituto Franciscano de Murcia.El perfil de su formación, trabajo y dedicación nos ayuda a comprender por qué a Francisco de A. Chavero no se le escapaba ningún detalle del pensamiento bonaventuriano. No había aspecto de su pensamiento filosófico, teológico, espiritual o franciscano que no conociera. Su obra, sus ediciones, las fuentes, los estudios e interpretaciones sobre el doctor Seráfico eran, no sólo conocidas por él, sino también estudiadas, pensadas e interpretadas. De todo lo que acabo de decir dan fe sus escritos y las extensísimas notas a pie de página que nos regalaba. Hablando de su trabajo siempre mostraba la visión de fondo que impregnaban sus estudios: el de historiador de la teología. Esto no significa que desde esta perspectiva histórica no fuera capaz de percibir y apuntar conceptos nuevos y visiones originales.Francisco de Asís Clavero Blanco colaboró en numerosas revistas como Verdad 1, Vida, Carthaginensia, Estudios Franciscanos, Doctor Seraphicus, Themata, Archivum Franciscanum Historicurn, etc. Era miembro de la Sociedad Escotista Internacional , del Centro di Studi Bonaventuriani , Asociación Hispánica de Estudios Franciscanos y compañero de la Sociedad Española de Filosofía Medieval . Me gustaría en estas páginas repasar aunque sea brevemente el legado intelectual de este pensador franciscano. (shrink)

RESUMENEl estudio se centra en la filosofía práctica cartesiana: la dimensión técnica y la moral. Una parte de su filosofía muchas veces poco estudiada. A lo largo del Discurso del Método, Descartes parece dialogar con Michel de Montaigne para superar su posición escéptica. Lo consigue desde el punto de vista teórico, pero no en relación a la acción moral. En ese ámbito, Descartes lejos de alejarse de las posiciones montañistas, las reproduce. Las reglas de la moral provisional ya están en (...) Montaigne y, como él, Descartes se tiene que conformar con lo probable en la acción moral.PALABRAS CLAVEDESCARTES, MONTAIGNE, ÁMBITO TEÓRICO, ÁMBITO PRÁCTICOABSTRACT This study is about Descartes’ philosophy: both its technical dimension and morality. Little attention has been paid to this part of his philosophy. Along the Discourse on Method, Descartes seems to speak with Michel de Montaigne with a view to overcome his sceptical position. He reaches this goal from the theoretical point of view, but not in the practical realm. In this area Descartes, far from moving away from Montaigne’s position, reproduces it. The rules of provisional morality are already in Montaigne and, like him, Descartes has to conform to a probabilistic approach in the moral action.KEY WORDSDESCARTES, MONTAIGNE, THEORETICAL REALM, PRACTICAL REALM. (shrink)

People's time is a limited resource and, in economic evaluations that adopt a societal perspective, it is important that it is valued and accounted for. Yet, in economic evaluations of interventions for children and young people (CYP), attempts to take into account the opportunity cost of their time are rare. To understand why this is the case, we need to first understand what views health economists hold in relation to CYP time, and what challenges they face in incorporating this in (...) their evaluations. We planned and carried out an international survey of health economists. We used a combination of approaches to identify potential survey respondents (the survey's sampling frame), we developed a questionnaire that sought to capture respondents' views and practice through close- and open-ended questions, we piloted the questionnaire through a series of cognitive interviews, and we e-mailed unique links to the final version of the questionnaire to 1956 individuals in the sampling frame. We analysed data using quantitative (descriptive and inferential statistics) and qualitative (thematic analysis) methods. We received 274 complete responses. Most respondents (87%) believe CYP time should be considered for inclusion in economic evaluations conducted from a societal perspective. However, they identify a number of obstacles to doing so, most prominently uncertainties around appropriate practice (e.g., when CYP's time should or should not be included in calculations), methodological gaps (e.g., what value to attach to CYP's time), and practical difficulties in measuring displaced time in CYP. Reporting on their own practice, most respondents found it challenging to consider CYP time in their studies, and stressed the need for clear guidance on when, and further research on how, to appropriately account for CYP's time in economic evaluations. We offer our views on how to move the topic forwards and make suggestions further research. (shrink)

The high levels of land use, inputs, and investment, along with the specific forms of organization and management that characterized Cuba's state extensive growth model during the 1980s, could not overcome the challenges posed by the integrated care required by the sugarcane crop and corresponding industrial activities. Starting in 1993, large state farms have been converted into Basic Units of Cooperative Production with some degree of autonomy. Although first-year production results are not satisfactory, it is too early to evaluate their (...) performance. Their establishment, however, is a step in the right direction to alleviate the problems that the previous forms of organization and management inherent to the state extensive growth model were unable to solve. (shrink)

Partiendo de una situación singular en lo referente a su origen y creación, la Universidad Politécnica de Madrid ha desarrollado procedimientos para identificar, ordenar y compartir los activos intelectuales de sus miembros con el fin de explotar sus recursos de conocimiento y competir en un entorno universitario cada vez más competitivo en la captación de buenos estudiantes, recursos de investigación y posición internacional. En este artículo se describen las principales actuaciones y logros que se han desarrollado desde el punto de (...) vista de los recursos educativos (integración de los nuevos estudiantes, desarrollo de competencias genéricas, plataformas experimentales a través de la red y recursos en abierto), espacios y estructura organizativa (Grupos de Innovación Educativa y políticas asociadas), sistemas de información (DataWareHouse y estudios basados en cuestionarios) y especialmente las personas como elemento insustituible en el proceso de gestión del conocimiento. Todo ello con un planteamiento integral que busca la combinación sinérgica de la capacidad de gestión de la información y recursos con la capacidad creativa e innovadora de los seres humanos. (shrink)